• Cohort, name
    Born in Bradford

    Cohort, abbreviation
    BIB

    Cohort, country
    United Kingdom

    Cohort, website
    http://www.borninbradford.nhs.uk

    Key reference
    Wright J, Small N, Raynor P, Tuffnell D, Bhopal R, Cameron N, Fairley L, Lawlor D, Parslow R, Petherick E, Pickett K, Waiblinger D, West J. Cohort profile: The Born in Bradford multi-ethnic family cohort study. International Journal of Epidemiology Aug 2013;1-14; DOI:10.1093/ije/dys112 WOS:000325167800010 ISSN: 0300-5771

    Date of filling in this questionnaire:
    2018-04-04

  • Principal investigator(s), name
    John Wright

    Principal investigator(s), e-mail address
    john.wright@bthft.nhs.uk

    Principal investigator(s), institution
    Bradford Institute for Health Research

    Contact person(s), name
    Rosie McEachan

    Contact person(s), e-mail address
    rosie.mceachan@bthft.nhs.uk

    Contact person(s), institution address
    Bradford Royal Infirmary, Duckworth Lane, Bradford BD9 6RJ

  • Main aim of cohort
    The broad aims of the Born in Bradford cohort study are to: • describe health and ill-health within a largely bi-ethnic population • identify modifiable causal pathways that promote well-being, or contribute to ill-health • develop, design, and evaluate interventions to promote health and wellbeing • develop a model for integrating operational, epidemiological and evaluative research into practice within the NHS, and other health related systems • build and strengthen the local research capacity

    Recruited number of:
    14000 children / 14000 mothers / 3000 fathers / 0 grand parents / 0 other family members

    Approximate proportion of source population included
    65

    Source population
    Other, please describeHospital-based, Bradford Royal Infirmary

  • Period of enrollment
    Start: 2007-01-01, End: 2010-12-24

    Enrollment period
    Pregnancy, week  to

    Enrollment criteria, please specify
    Booked for delivery at Bradford Royal Infirmary

    Exclusion criteria, please specify
    women who plan to move out of Bradford before the birth

    Planned age of children at end of follow-up
    unrestricted yearsLife-long / unrestricted
General information ---------- Child age (years) at assessment ----------
<1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Home addressXXXXXXXX
School addressXXXXX
Birth outcomes
Birth weightX
Birth length
Gestational age at birthX
Apgar scoreX
Congenital malformationsX
Stillbirth (>= 22 weeks)X
Child’s sexX
Head circumference
Biparietal diameter
Child exposures ---------- Child age (years) at assessment ----------
<1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Breast feedingXX
DietXXXXX
Dietary supplements
Childcare attendanceXXX
Active smoking
Passive smokingXXXX
Alcohol consumption
Physical activityXXXX
Substance use
Medicine intakeXXXXXXXXXX
VaccinationsXXX
Psychological distress (e.g. bullying)
Air pollutionXXXX
Access to green spacesXX
Built environmentXX
NoiseXXX
Radiation, electromagnetic fields
Water contamination
PetsXX
Farm animal exposure
Biomarkers of exposure
Mercury
Lead
Cadmium
Arsenic
Other metals
Polychlorinated biphenyl esters
Dicloro difenil tricloroetano
Hexachlorobenzene
Brominated flame retardants
Perflouralkyl compounds
Bisphenol A
Other bisphenols
Parabens
Benzophenones
Triclosan
Phthalates
Cotinine
Child development and health ---------- Child age (years) at assessment ----------
<1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Anthropometry
WeightXXXXX
HeightXXXXXX
Head circumferenceXXX
Abdominal circumferenceXX
Arm circumferenceXX
Wrist circumference
Waist circumference
Clinical examinations
Blood pressure
Carotida intima media thickness
Pulse wave velocity
Cardiac ultrasound
Renal ultrasoundX
Brain MRI
Other MRI
DEXA‐scan resultsX
Skin folds
Bio impedenceXX
Oscilometry
SpirometryX
Skin prick testX
Bronchial challenge test
Reversibility test
Dental observationsXX
Mental and neurological development
Cognitive functionX
School performanceX
LanguageX
ADHDX
AutismX
Sleep disturbancesXXX
Mental healthX
Respiratory health
AsthmaX
AllergyX
Allergic rhinitisX
EczemaX
Respiratory tract infectionsX
Senses
Vision
Hearing
Musculo-skeletal health
Back pain
Neck pain
Growing pains
Sexual maturation
Tanner stage
Pubertal development stage
Age at menarche
Age at voice change
2D/4D digit ratio
Nocturnal ejaculation
Acne
Other health outcomes
CancerXXX
DiabetesXXX
Congenital anomaliesXXXX
Biomarkers of health
Nephrology (e.g. creatinine, albumin)
Thyroid hormones
Inflammatory markers (e.g. C-reactive protein cytokines)
Immunologic markers (e.g. immunoglobulines)
Cortisol
Vitamines and micronutrients
Gonadal axis hormones (e.g. testosterone, estradiol)
Metabolism (e.g. cholesterol, LDL, HDL, insulin, triglycerides)X
MetabolomicsX
DNA methylationX
Transcriptomics (mRNA, miRNA)
Genome-wide association study (GWAS)X
Child biological samples ---------- Child age (years) at sampling ----------
At birth 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Whole bloodXXX
SerumXXX
PlasmaXXXXXX
Buffy coatX
Urine
Hair
Teeth
Nails
Saliva
Purified DNAX
Purified RNA
Red blood cells
Umbilical cord blood/tissueX
Blood smear
Faeces/meconium
Exhaled breathe condensate
Sputum induction
Placenta
General information
Pre-pregnancy During pregnancy <1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
EducationX
IncomeX
Employment status
Job title
Single parenthoodX
Home address
Work address
Maternal characteristics related to the index pregnancy/child
Age at birthX
EthnicityX
Country of birth
Planned pregnancy
Time to pregnancy
Fertility treatment
Prior spontaneous abortion (<22w)
Prior birthsX
Ultrasound measurements
Doppler measurements
PreeclampsiaX
Gestational diabetes
Gestational hypertension
Gestational durationX
Mode of deliveryX
Prenatal diagnosticsX
Medical termination of pregnancy
Maternal Exposures ---------- Timing of assessment ----------
Pre-pregnancy First trimester Second trimester Third trimester Post pregnancy
DietXX
Dietary supplementsXX
Active smokingXX
Passive smokingXX
Alcohol consumptionXX
Physical activityXX
Substance use
Medicine intakeXX
Coffee drinkingX
Psychological distress (e.g. life-events, health behaviors, perceived stress)XX
Occupational exposuresX
Heavy lifts
Work hours
Air pollutionX
Access to green spaces
Built environment
Noise
Radiation, electromagnetic fields
Water contamination
Binge drinkingXX
Pets
Farm animal exposure
Biomarkers of exposure
Mercury
Lead
Cadmium
Arsenic
Other metals
Polychlorinated biphenyl esters
Dicloro difenil tricloroetano
Hexachlorobenzene
Brominated flame retardants
Perflouralkyl compounds
Bisphenol A
Other bisphenols
Parabens
Benzophenones
Triclosan
Phthalates
Cotinine
Maternal health ---------- Timing of assessment ----------
Pre-pregnancy First trimester Second trimester Third trimester Post pregnancy
Anthropometry
WeightXX
HeightX
Waist circumference
Clinical examinations
Blood pressureX
Carotida intima media thickness
Pulse wave velocity
DEXA scans
Bioimpedence
Mental and neurological development
Mental healthXX
Cognitive function (e.g. intelligence quotient)
Respiratory health
Asthma
Allergy
Musculo‐skeletal diseaseXX
Back pain
Neck pain
Arthritis
Other health outcomes
CancerXX
DiabetesXX
Cardio‐vascular diseaseXX
Family history of chronic disease
Infectious diseaseXX
Fever
Autoimmune diseaseXX
Urinary symptoms
Sexual problems
Sleep disturbance
Biomarkers of health
Nephrology (e.g. creatinine, albumin)
Thyroid hormones
Inflammatory markers (e.g. C-reactive protein cytokines)
Immunologic markers (e.g. immunoglobulines)
Cortisol
Vitamines and micronutrients
Gonadal axis hormones (e.g. testosterone, estradiol)
Metabolism (e.g. cholesterol, LDL, HDL, insulin, triglycerides)
Metabolomics
DNA methylation
Transcriptomics (mRNA, miRNA)
Genome-wide association study (GWAS)
Maternal biological samples ---------- Timing of sampling ----------
Pre-pregnancy First trimester Second trimester Third trimester Post pregnancy
Breast milk
Whole bloodX
SerumX
Plasma
Buffy coat
UrineX
Hair
Nails
Saliva
Purified DNA
Purified RNA
Red blood cells
Faeces
General information
Pre-pregnancy During pregnancy <1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
EducationX
Income
Employment status
Job title
Single parenthood
Home address
Work address
Paternal characteristics related to the index pregnancy/child
Fertility treatment
Age at child's birth
EthnicityX
Country of birth
Paternal exposures ---------- Timing of assessment ----------
Pre-pregnancy During pregnancy Post pregnancy
Diet
Dietary supplements
Active smokingX
Passive smokingX
Alcohol consumptionX
Physical activity
Substance use
Medicine intake
Coffee drinking
Psychological distress (e.g. life-events, health behaviors, perceived stress)
Occupational exposuresX
Heavy lifts
Work hours
Air pollution
Access to green spaces
Built environment
Noise
Radiation, electromagnetic fields
Water contamination
Binge drinking
Pets
Farm animal exposure
Biomarkers of exposure
Mercury
Lead
Cadmium
Arsenic
Other metals
Polychlorinated biphenyl esters
Dicloro difenil tricloroetano
Hexachlorobenzene
Brominated flame retardants
Perflouralkyl compounds
Bisphenol A
Other bisphenols
Parabens
Benzophenones
Triclosan
Phthalates
Cotinine
Paternal health ---------- Timing of assessment ----------
Pre-pregnancy During pregnancy Post pregnancy
Anthropometry
WeightX
HeightX
Waist circumference
Clinical examinations
Blood pressure
Carotida intima media thickness
Pulse wave velocity
DEXA scans
Bio impedence
Mental and neurological development
Mental health
Cognitive function (e.g. intelligence quotient)
Respiratory health
Asthma
Allergy
Musculo‐skeletal disease
Back pain
Neck pain
Arthritis
Other health outcomes
Cancer
Diabetes
Cardio‐vascular disease
Family history of chronic disease
Infectious disease
Fever
Autoimmune disease
Urinary symptoms
Sexual problems
Sleep disturbance
Biomarkers of health
Nephrology (e.g. creatinine, albumin)
Thyroid hormones
Inflammatory markers (e.g. C-reactive protein cytokines)
Immunologic markers (e.g. immunoglobulines)
Cortisol
Vitamines and micronutrients
Gonadal axis hormones (e.g. testosterone, estradiol)
Metabolism (e.g. cholesterol, LDL, HDL, insulin, triglycerides)
Metabolomics
DNA methylation
Transcriptomics (mRNA, miRNA)
Genome-wide association study (GWAS)
Paternal biological samples ---------- Timing of sampling ----------
Pre-pregnancy During pregnancy Post pregnancy
Semen
Whole blood
Serum
Plasma
Buffy coat
Urine
Hair
Nails
SalivaX
Purified DNA
Purified RNA
Red blood cells
Faeces
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