• Cohort, name
    Norwegian Mother and Child Cohort Study

    Cohort, abbreviation
    MoBa

    Cohort, country
    Norway (Norge)

    Cohort, website
    http://www.fhi.no/moba-en

    Key reference
    Magnus P, Irgens LM, Haug K, Nystad W, Skjaerven R, Stoltenberg C; MoBa Study Group. Cohort profile: the Norwegian Mother and Child Cohort Study (MoBa). nt J Epidemiol. 2006 Oct;35(5):1146-50.

    Date of filling in this questionnaire:
    2012-08-16

  • Principal investigator(s), name
    Per Magnus

    Principal investigator(s), e-mail address
    per.magnus@fhi.no

    Principal investigator(s), institution
    Norwegian Institute of Public Health

    Contact person(s), name
    Charlotte Birke

    Contact person(s), e-mail address
    charlotte.birke@fhi.no

    Contact person(s), institution address
    Norwegian Institute of Public Health

  • Main aim of cohort
    The main aim of the study is to find causes of diseases. Additional aims are to detect early signs of disease and to describe the development of diseases. A broader discussion of aims and methods is given in Magnus P et al. Cohort profile: The Norwegian Mother and Child Cohort Study. Int J Epidemiol 2006;35:1146-50.

    Recruited number of:
    108500 children / 90700 mothers / 72100 fathers / 0 grand parents / 0 other family members

    Approximate proportion of source population included
    38

    Source population
    Nation-based

  • Period of enrollment
    Start: 1999-01-01, End: 2008-12-31

    Enrollment period
    Pregnancy, week 17 to 20

    Enrollment criteria, please specify
    The target population were all pregnant women in Norway during the inclusion time who returned informed consent. Tathers were informed and recruited through the women. All participants need basic knowledg of Norwegioan to complete the questionnaires

    Exclusion criteria, please specify
    Children not born in Norway. Mother without basic knowledg of Norwegian

    Planned age of children at end of follow-up
    Life-long / unrestricted
General information ---------- Child age (years) at assessment ----------
<1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Home address
School address
Birth outcomes
Birth weightX
Birth lengthX
Gestational age at birthX
Apgar scoreX
Congenital malformationsX
Stillbirth (>= 22 weeks)X
Child’s sex
Head circumference
Biparietal diameter
Child exposures ---------- Child age (years) at assessment ----------
<1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Breast feedingXX
DietXXXXX
Dietary supplements
Childcare attendanceXXXX
Active smoking
Passive smokingXXXX
Alcohol consumption
Physical activityXXXXX
Substance use
Medicine intake
Vaccinations
Psychological distress (e.g. bullying)
Air pollution
Access to green spaces
Built environment
Noise
Radiation, electromagnetic fields
Water contamination
Pets
Farm animal exposure
Biomarkers of exposure
Mercury
Lead
Cadmium
Arsenic
Other metals
Polychlorinated biphenyl esters
Dicloro difenil tricloroetano
Hexachlorobenzene
Brominated flame retardants
Perflouralkyl compounds
Bisphenol A
Other bisphenols
Parabens
Benzophenones
Triclosan
Phthalates
Cotinine
Child development and health ---------- Child age (years) at assessment ----------
<1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Anthropometry
WeightXXXXXXX
HeightXXXXXXX
Head circumferenceX
Abdominal circumference
Arm circumference
Wrist circumference
Waist circumference
Clinical examinations
Blood pressure
Carotida intima media thickness
Pulse wave velocity
Cardiac ultrasound
Renal ultrasound
Brain MRI
Other MRI
DEXA‐scan results
Skin folds
Bio impedence
Oscilometry
Spirometry
Skin prick test
Bronchial challenge test
Reversibility test
Dental observations
Mental and neurological development
Cognitive function
School performanceXX
LanguageXXXX
ADHD
Autism
Sleep disturbancesXXXXX
Mental healthXX
Respiratory health
Asthma
Allergy
Allergic rhinitis
Eczema
Respiratory tract infections
Senses
Vision
Hearing
Musculo-skeletal health
Back pain
Neck pain
Growing pains
Sexual maturation
Tanner stage
Pubertal development stage
Age at menarche
Age at voice change
2D/4D digit ratio
Nocturnal ejaculation
Acne
Other health outcomes
CancerXX
DiabetesXXX
Congenital anomaliesXXXXX
Biomarkers of health
Nephrology (e.g. creatinine, albumin)
Thyroid hormones
Inflammatory markers (e.g. C-reactive protein cytokines)
Immunologic markers (e.g. immunoglobulines)
Cortisol
Vitamines and micronutrients
Gonadal axis hormones (e.g. testosterone, estradiol)
Metabolism (e.g. cholesterol, LDL, HDL, insulin, triglycerides)
Metabolomics
DNA methylation
Transcriptomics (mRNA, miRNA)
Genome-wide association study (GWAS)
Child biological samples ---------- Child age (years) at sampling ----------
At birth 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Whole bloodX
Serum
Plasma
Buffy coat
Urine
Hair
TeethX
Nails
Saliva
Purified DNAX
Purified RNA
Red blood cells
Umbilical cord blood/tissueX
Blood smear
Faeces/meconium
Exhaled breathe condensate
Sputum induction
Placenta
General information
Pre-pregnancy During pregnancy <1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
EducationX
Income
Employment status
Job title
Single parenthoodX
Home address
Work address
Maternal characteristics related to the index pregnancy/child
Age at birthX
Ethnicity
Country of birth
Planned pregnancyX
Time to pregnancyX
Fertility treatmentX
Prior spontaneous abortion (<22w)X
Prior birthsX
Ultrasound measurements
Doppler measurements
PreeclampsiaX
Gestational diabetes
Gestational hypertension
Gestational durationX
Mode of deliveryX
Prenatal diagnosticsX
Medical termination of pregnancyX
Maternal Exposures ---------- Timing of assessment ----------
Pre-pregnancy First trimester Second trimester Third trimester Post pregnancy
DietXX
Dietary supplementsXXX
Active smokingXXXXX
Passive smokingXXXXX
Alcohol consumptionXXXXX
Physical activityXXXX
Substance useXXXX
Medicine intakeXXXXX
Coffee drinkingXXX
Psychological distress (e.g. life-events, health behaviors, perceived stress)XXX
Occupational exposuresX
Heavy liftsXX
Work hours
Air pollutionX
Access to green spaces
Built environment
NoiseXX
Radiation, electromagnetic fields
Water contaminationXX
Binge drinkingXXXXX
Pets
Farm animal exposure
Biomarkers of exposure
Mercury
Lead
Cadmium
Arsenic
Other metals
Polychlorinated biphenyl esters
Dicloro difenil tricloroetano
Hexachlorobenzene
Brominated flame retardants
Perflouralkyl compounds
Bisphenol A
Other bisphenols
Parabens
Benzophenones
Triclosan
Phthalates
Cotinine
Maternal health ---------- Timing of assessment ----------
Pre-pregnancy First trimester Second trimester Third trimester Post pregnancy
Anthropometry
WeightXXXX
HeightXX
Waist circumference
Clinical examinations
Blood pressureX
Carotida intima media thickness
Pulse wave velocity
DEXA scans
Bioimpedence
Mental and neurological development
Mental healthXXXXX
Cognitive function (e.g. intelligence quotient)
Respiratory health
Asthma
AllergyXXX
Musculo‐skeletal diseaseXXXXX
Back pain
Neck pain
Arthritis
Other health outcomes
CancerXXX
DiabetesXXX
Cardio‐vascular diseaseXXX
Family history of chronic disease
Infectious diseaseXXXXX
FeverXXXX
Autoimmune diseaseXXX
Urinary symptoms
Sexual problems
Sleep disturbance
Biomarkers of health
Nephrology (e.g. creatinine, albumin)
Thyroid hormones
Inflammatory markers (e.g. C-reactive protein cytokines)
Immunologic markers (e.g. immunoglobulines)
Cortisol
Vitamines and micronutrients
Gonadal axis hormones (e.g. testosterone, estradiol)
Metabolism (e.g. cholesterol, LDL, HDL, insulin, triglycerides)
Metabolomics
DNA methylation
Transcriptomics (mRNA, miRNA)
Genome-wide association study (GWAS)
Maternal biological samples ---------- Timing of sampling ----------
Pre-pregnancy First trimester Second trimester Third trimester Post pregnancy
Breast milk
Whole bloodXX
Serum
Plasma
Buffy coat
UrineX
Hair
Nails
Saliva
Purified DNAXX
Purified RNA
Red blood cells
Faeces
General information
Pre-pregnancy During pregnancy <1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
EducationX
IncomeX
Employment status
Job title
Single parenthood
Home address
Work address
Paternal characteristics related to the index pregnancy/child
Fertility treatment
Age at child's birthX
Ethnicity
Country of birth
Paternal exposures ---------- Timing of assessment ----------
Pre-pregnancy During pregnancy Post pregnancy
DietX
Dietary supplements
Active smokingXXX
Passive smoking
Alcohol consumptionXX
Physical activityX
Substance useXX
Medicine intake
Coffee drinking
Psychological distress (e.g. life-events, health behaviors, perceived stress)X
Occupational exposuresX
Heavy lifts
Work hours
Air pollution
Access to green spaces
Built environment
Noise
Radiation, electromagnetic fields
Water contamination
Binge drinking
Pets
Farm animal exposure
Biomarkers of exposure
Mercury
Lead
Cadmium
Arsenic
Other metals
Polychlorinated biphenyl esters
Dicloro difenil tricloroetano
Hexachlorobenzene
Brominated flame retardants
Perflouralkyl compounds
Bisphenol A
Other bisphenols
Parabens
Benzophenones
Triclosan
Phthalates
Cotinine
Paternal health ---------- Timing of assessment ----------
Pre-pregnancy During pregnancy Post pregnancy
Anthropometry
WeightX
HeightX
Waist circumference
Clinical examinations
Blood pressure
Carotida intima media thickness
Pulse wave velocity
DEXA scans
Bio impedence
Mental and neurological development
Mental healthXX
Cognitive function (e.g. intelligence quotient)
Respiratory health
Asthma
Allergy
Musculo‐skeletal diseaseXX
Back pain
Neck pain
Arthritis
Other health outcomes
CancerXX
DiabetesXX
Cardio‐vascular diseaseXX
Family history of chronic disease
Infectious diseaseXX
Fever
Autoimmune disease
Urinary symptoms
Sexual problems
Sleep disturbance
Biomarkers of health
Nephrology (e.g. creatinine, albumin)
Thyroid hormones
Inflammatory markers (e.g. C-reactive protein cytokines)
Immunologic markers (e.g. immunoglobulines)
Cortisol
Vitamines and micronutrients
Gonadal axis hormones (e.g. testosterone, estradiol)
Metabolism (e.g. cholesterol, LDL, HDL, insulin, triglycerides)
Metabolomics
DNA methylation
Transcriptomics (mRNA, miRNA)
Genome-wide association study (GWAS)
Paternal biological samples ---------- Timing of sampling ----------
Pre-pregnancy During pregnancy Post pregnancy
Semen
Whole bloodX
Serum
Plasma
Buffy coat
Urine
Hair
Nails
Saliva
Purified DNAX
Purified RNA
Red blood cells
Faeces
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