• Cohort, name
    ShengJing Birth Cohort

    Cohort, abbreviation
    SJBC

    Cohort, country
    China (中国)

    Date of filling in this questionnaire:
    2018-03-28

  • Principal investigator(s), name
    Prof Dr Zhengwei Yuan

    Principal investigator(s), e-mail address
    yuanzw@sj-hospital.org

    Principal investigator(s), institution
    Shengjing Hospital, China Medical University

    Contact person(s), name
    Shanshan Jia

    Contact person(s), e-mail address
    jsscmu@163.com

    Contact person(s), institution address
    Shengjing Hospital, China Medical University

  • Main aim of cohort
    To examine the effects of genetic, nutritional, environmental, and social factors on maternal, child, and adolescent health outcomes. The research results will help promote and improve the health status of the next generation of children and their families in China and may even be extended to other countries or regions.

    Recruited number of:
    20000 children / 20000 mothers / 20000 fathers / 0 grand parents / 0 other family members

    Approximate proportion of source population included
    0

    Source population
    Region-based

  • Period of enrollment
    Start: 2017-05-10, End: 0000-00-00

    Enrollment period
    Pregnancy, week 1 to 20

    Enrollment criteria, please specify
    meeting the following three conditions: 1, pregnant women 20 weeks before gestation 2, planning to give birth at shengjing hospital 3, residing in Northeast China and no relocation plan within 3 years of their children

    Exclusion criteria, please specify
    Not familiar with Chinese language in word and writing.

    Planned age of children at end of follow-up
    18 years
General information ---------- Child age (years) at assessment ----------
<1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Home addressXXXXXXXXXXXXXXXXXXX
School addressXXXXXXXXXXXXXXXXXXX
Birth outcomes
Birth weightX
Birth lengthX
Gestational age at birthX
Apgar scoreX
Congenital malformationsX
Stillbirth (>= 22 weeks)X
Child’s sexX
Head circumferenceX
Biparietal diameterX
Child exposures ---------- Child age (years) at assessment ----------
<1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Breast feedingXXXX
DietXXXXXXXXXXXXXXXXXXX
Dietary supplementsXXXXXXXXXXXXXXXXXXX
Childcare attendanceXXXXXXX
Active smokingXXXXXXXXX
Passive smokingXXXXXXXXXXXXXXXXXXX
Alcohol consumptionXXXXXXXXX
Physical activityXXXXXXXXXXXXXXXXXXX
Substance useXXXXXXXXX
Medicine intakeXXXXXXXXXXXXXXXXXXX
VaccinationsXXXXXXXXXXXXXXXXXXX
Psychological distress (e.g. bullying)XXXXXXXXXXXXXXXXXXX
Air pollutionXXXXXXXXXXXXXXXXXXX
Access to green spacesXXXXXXXXXXXXXXXXXXX
Built environmentXXXXXXXXXXXXXXXXXXX
NoiseXXXXXXXXXXXXXXXXXXX
Radiation, electromagnetic fieldsXXXXXXXXXXXXXXXXXXX
Water contaminationXXXXXXXXXXXXXXXXXXX
PetsXXXXXXXXXXXXXXXXXXX
Farm animal exposureXXXXXXXXXXXXXXXXXXX
Biomarkers of exposure
MercuryXXXXXXXXXXXXXXXXXXX
LeadXXXXXXXXXXXXXXXXXXX
CadmiumXXXXXXXXXXXXXXXXXXX
ArsenicXXXXXXXXXXXXXXXXXXX
Other metalsXXXXXXXXXXXXXXXXXXX
Polychlorinated biphenyl estersXXXXXXXXXXXXXXXXXXX
Dicloro difenil tricloroetanoXXXXXXXXXXXXXXXXXXX
HexachlorobenzeneXXXXXXXXXXXXXXXXXXX
Brominated flame retardantsXXXXXXXXXXXXXXXXXXX
Perflouralkyl compoundsXXXXXXXXXXXXXXXXXXX
Bisphenol AXXXXXXXXXXXXXXXXXXX
Other bisphenolsXXXXXXXXXXXXXXXXXXX
ParabensXXXXXXXXXXXXXXXXXXX
BenzophenonesXXXXXXXXXXXXXXXXXXX
TriclosanXXXXXXXXXXXXXXXXXXX
PhthalatesXXXXXXXXXXXXXXXXXXX
CotinineXXXXXXXXXXXXXXXXXXX
Child development and health ---------- Child age (years) at assessment ----------
<1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Anthropometry
WeightXXXXXXXXXXXXXXXXXXX
HeightXXXXXXXXXXXXXXXXXXX
Head circumferenceXXXXXXXXXXXXXXXXXXX
Abdominal circumferenceXXXXXXXXXXXXXXXXXXX
Arm circumferenceXXXXXXXXXXXXXXXXXXX
Wrist circumferenceXXXXXXXXXXXXXXXXXXX
Waist circumferenceXXXXXXXXXXXXXXXXXXX
Clinical examinations
Blood pressureXXXXXXXXXXXXXXXXXXX
Carotida intima media thicknessXXXXXXXXXXXXXXXXXXX
Pulse wave velocityXXXXXXXXXXXXXXXXXXX
Cardiac ultrasoundXXXXXXXXXXXXXXXXXXX
Renal ultrasoundXXXXXXXXXXXXXXXXXXX
Brain MRIXXXXXXXXXXXXXXXXXXX
Other MRIXXXXXXXXXXXXXXXXXXX
DEXA‐scan resultsXXXXXXXXXXXXXXXXXXX
Skin foldsXXXXXXXXXXXXXXXXXXX
Bio impedenceXXXXXXXXXXXXXXXXXXX
OscilometryXXXXXXXXXXXXXXXXXXX
SpirometryXXXXXXXXXXXXXXXXXXX
Skin prick testXXXXXXXXXXXXXXXXXXX
Bronchial challenge testXXXXXXXXXXXXXXXXXXX
Reversibility testXXXXXXXXXXXXXXXXXXX
Dental observationsXXXXXXXXXXXXXXXXXXX
Mental and neurological development
Cognitive functionXXXXXXXXXXXXXXXXXXX
School performanceXXXXXXXXXXXXXXX
LanguageXXXXXXXXXXXXXXXXXX
ADHDXXXXXXXXXXXXXXXXXXX
AutismXXXXXXXXXXXXXXXXXXX
Sleep disturbancesXXXXXXXXXXXXXXXXXXX
Mental healthXXXXXXXXXXXXXXXXXXX
Respiratory health
AsthmaXXXXXXXXXXXXXXXXXXX
AllergyXXXXXXXXXXXXXXXXXXX
Allergic rhinitisXXXXXXXXXXXXXXXXXXX
EczemaXXXXXXXXXXXXXXXXXXX
Respiratory tract infectionsXXXXXXXXXXXXXXXXXXX
Senses
VisionXXXXXXXXXXXXXXXXXXX
HearingXXXXXXXXXXXXXXXXXXX
Musculo-skeletal health
Back painXXXXXXXXXXXXXXXXXXX
Neck painXXXXXXXXXXXXXXXXXXX
Growing painsXXXXXXXXXXXXXXXXXXX
Sexual maturation
Tanner stageXXXXXXXXXXXXXXXXXXX
Pubertal development stageXXXXXXXXXXXXXXXXXXX
Age at menarcheXXXXXXXXXX
Age at voice changeXXXXXXXXXXXXXXXXXXX
2D/4D digit ratioXXXXXXXXXXXXXXXXXXX
Nocturnal ejaculationXXXXXXXXXXXXXXXXXXX
AcneXXXXXXXXXXXXXXXXXXX
Other health outcomes
CancerXXXXXXXXXXXXXXXXXXX
DiabetesXXXXXXXXXXXXXXXXXXX
Congenital anomaliesXXXXXXXXXXXXXXXXXXX
Biomarkers of health
Nephrology (e.g. creatinine, albumin)XXXXXXXXXXXXXXXXXXX
Thyroid hormonesXXXXXXXXXXXXXXXXXXX
Inflammatory markers (e.g. C-reactive protein cytokines)XXXXXXXXXXXXXXXXXXX
Immunologic markers (e.g. immunoglobulines)XXXXXXXXXXXXXXXXXXX
CortisolXXXXXXXXXXXXXXXXXXX
Vitamines and micronutrientsXXXXXXXXXXXXXXXXXXX
Gonadal axis hormones (e.g. testosterone, estradiol)XXXXXXXXXXXXXXXXXXX
Metabolism (e.g. cholesterol, LDL, HDL, insulin, triglycerides)XXXXXXXXXXXXXXXXXXX
MetabolomicsXXXXXXXXXXXXXXXXXXX
DNA methylationXXXXXXXXXXXXXXXXXXX
Transcriptomics (mRNA, miRNA)XXXXXXXXXXXXXXXXXXX
Genome-wide association study (GWAS)XXXXXXXXXXXXXXXXXXX
Child biological samples ---------- Child age (years) at sampling ----------
At birth 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Whole bloodXXXXXXXXXXXXXXXXXXXX
SerumXXXXXXXXXXXXXXXXXXXX
PlasmaXXXXXXXXXXXXXXXXXXXX
Buffy coatXXXXXXXXXXXXXXXXXXXX
UrineXXXXXXXXXXXXXXXXXXXX
HairXXXXXXXXXXXXXXXXXXXX
TeethXXXXXXXXXXXXXXXXXXX
NailsXXXXXXXXXXXXXXXXXXXX
SalivaXXXXXXXXXXXXXXXXXXXX
Purified DNAXXXXXXXXXXXXXXXXXXXX
Purified RNAXXXXXXXXXXXXXXXXXXXX
Red blood cellsXXXXXXXXXXXXXXXXXXXX
Umbilical cord blood/tissueX
Blood smearXXXXXXXXXXXXXXXXXXXX
Faeces/meconiumXXXXXXXXXXXXXXXXXXXX
Exhaled breathe condensateXXXXXXXXXXXXXXXXXXXX
Sputum inductionXXXXXXXXXXXXXXXXXXXX
PlacentaX
General information
Pre-pregnancy During pregnancy <1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
EducationXXXXXXXXXXXXXXXXXXXXX
IncomeXXXXXXXXXXXXXXXXXXXXX
Employment statusXXXXXXXXXXXXXXXXXXXXX
Job titleXXXXXXXXXXXXXXXXXXXXX
Single parenthoodXXXXXXXXXXXXXXXXXXXXX
Home addressXXXXXXXXXXXXXXXXXXXXX
Work addressXXXXXXXXXXXXXXXXXXXXX
Maternal characteristics related to the index pregnancy/child
Age at birthX
EthnicityX
Country of birthX
Planned pregnancyX
Time to pregnancyX
Fertility treatmentX
Prior spontaneous abortion (<22w)X
Prior birthsX
Ultrasound measurementsX
Doppler measurementsX
PreeclampsiaX
Gestational diabetesX
Gestational hypertensionX
Gestational durationX
Mode of deliveryX
Prenatal diagnosticsX
Medical termination of pregnancyX
Maternal Exposures ---------- Timing of assessment ----------
Pre-pregnancy First trimester Second trimester Third trimester Post pregnancy
DietXXXXX
Dietary supplementsXXXXX
Active smokingXXXXX
Passive smokingXXXXX
Alcohol consumptionXXXXX
Physical activityXXXXX
Substance useXXXXX
Medicine intakeXXXXX
Coffee drinkingXXXXX
Psychological distress (e.g. life-events, health behaviors, perceived stress)XXXXX
Occupational exposuresXXXXX
Heavy liftsXXXXX
Work hoursXXXXX
Air pollutionXXXXX
Access to green spacesXXXXX
Built environmentXXXXX
NoiseXXXXX
Radiation, electromagnetic fieldsXXXXX
Water contaminationXXXXX
Binge drinkingXXXXX
PetsXXXXX
Farm animal exposureXXXXX
Biomarkers of exposure
MercuryXXXXX
LeadXXXXX
CadmiumXXXXX
ArsenicXXXXX
Other metalsXXXXX
Polychlorinated biphenyl estersXXXXX
Dicloro difenil tricloroetanoXXXXX
HexachlorobenzeneXXXXX
Brominated flame retardantsXXXXX
Perflouralkyl compoundsXXXXX
Bisphenol AXXXXX
Other bisphenolsXXXXX
ParabensXXXXX
BenzophenonesXXXXX
TriclosanXXXXX
PhthalatesXXXXX
CotinineXXXXX
Maternal health ---------- Timing of assessment ----------
Pre-pregnancy First trimester Second trimester Third trimester Post pregnancy
Anthropometry
WeightXXXXX
HeightXXXXX
Waist circumferenceXXXXX
Clinical examinations
Blood pressureXXXXX
Carotida intima media thicknessXXXXX
Pulse wave velocityXXXXX
DEXA scansX
BioimpedenceX
Mental and neurological development
Mental healthXXXXX
Cognitive function (e.g. intelligence quotient)XXXXX
Respiratory health
AsthmaXXXXX
AllergyXXXXX
Musculo‐skeletal disease
Back painXXXXX
Neck painXXXXX
ArthritisXXXXX
Other health outcomes
CancerXXXXX
DiabetesXXXXX
Cardio‐vascular diseaseXXXXX
Family history of chronic diseaseXXXXX
Infectious diseaseXXXXX
FeverXXXXX
Autoimmune diseaseXXXXX
Urinary symptomsXXXXX
Sexual problemsXXXXX
Sleep disturbanceXXXXX
Biomarkers of health
Nephrology (e.g. creatinine, albumin)XXXXX
Thyroid hormonesXXXXX
Inflammatory markers (e.g. C-reactive protein cytokines)XXXXX
Immunologic markers (e.g. immunoglobulines)XXXXX
CortisolXXXXX
Vitamines and micronutrientsXXXXX
Gonadal axis hormones (e.g. testosterone, estradiol)XXXXX
Metabolism (e.g. cholesterol, LDL, HDL, insulin, triglycerides)XXXXX
MetabolomicsXXXXX
DNA methylationXXXXX
Transcriptomics (mRNA, miRNA)XXXXX
Genome-wide association study (GWAS)XXXXX
Maternal biological samples ---------- Timing of sampling ----------
Pre-pregnancy First trimester Second trimester Third trimester Post pregnancy
Breast milkX
Whole bloodXXXXX
SerumXXXXX
PlasmaXXXXX
Buffy coatXXXXX
UrineXXXXX
HairXXXXX
NailsXXXXX
SalivaXXXXX
Purified DNAXXXX
Purified RNAXXXX
Red blood cellsXXXXX
FaecesXXXXX
General information
Pre-pregnancy During pregnancy <1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
EducationXXXXXXXXXXXXXXXXXXXXX
IncomeXXXXXXXXXXXXXXXXXXXXX
Employment statusXXXXXXXXXXXXXXXXXXXXX
Job titleXXXXXXXXXXXXXXXXXXXXX
Single parenthoodXXXXXXXXXXXXXXXXXXXXX
Home addressXXXXXXXXXXXXXXXXXXXXX
Work addressXXXXXXXXXXXXXXXXXXXXX
Paternal characteristics related to the index pregnancy/child
Fertility treatmentX
Age at child's birthX
EthnicityX
Country of birthX
Paternal exposures ---------- Timing of assessment ----------
Pre-pregnancy During pregnancy Post pregnancy
DietXXX
Dietary supplementsXXX
Active smokingXXX
Passive smokingXXX
Alcohol consumptionXXX
Physical activityXXX
Substance useXXX
Medicine intakeXXX
Coffee drinkingXXX
Psychological distress (e.g. life-events, health behaviors, perceived stress)XXX
Occupational exposuresXXX
Heavy liftsXXX
Work hoursXXX
Air pollutionXXX
Access to green spacesXXX
Built environmentXXX
NoiseXXX
Radiation, electromagnetic fieldsXXX
Water contaminationXXX
Binge drinkingXXX
PetsXXX
Farm animal exposureXXX
Biomarkers of exposure
MercuryXXX
LeadXXX
CadmiumXXX
ArsenicXXX
Other metalsXXX
Polychlorinated biphenyl estersXXX
Dicloro difenil tricloroetanoXXX
HexachlorobenzeneXXX
Brominated flame retardantsXXX
Perflouralkyl compoundsXXX
Bisphenol AXXX
Other bisphenolsXXX
ParabensXXX
BenzophenonesXXX
TriclosanXXX
PhthalatesXXX
CotinineXXX
Paternal health ---------- Timing of assessment ----------
Pre-pregnancy During pregnancy Post pregnancy
Anthropometry
WeightXXX
HeightXXX
Waist circumferenceXXX
Clinical examinations
Blood pressureXXX
Carotida intima media thicknessXXX
Pulse wave velocityXXX
DEXA scansXXX
Bio impedenceXXX
Mental and neurological development
Mental healthXXX
Cognitive function (e.g. intelligence quotient)XXX
Respiratory health
AsthmaXXX
AllergyXXX
Musculo‐skeletal disease
Back painXXX
Neck painXXX
ArthritisXXX
Other health outcomes
CancerXXX
DiabetesXXX
Cardio‐vascular diseaseXXX
Family history of chronic diseaseXXX
Infectious diseaseXXX
FeverXXX
Autoimmune diseaseXXX
Urinary symptomsXXX
Sexual problemsXXX
Sleep disturbanceXXX
Biomarkers of health
Nephrology (e.g. creatinine, albumin)XXX
Thyroid hormonesXXX
Inflammatory markers (e.g. C-reactive protein cytokines)XXX
Immunologic markers (e.g. immunoglobulines)XXX
CortisolXXX
Vitamines and micronutrientsXXX
Gonadal axis hormones (e.g. testosterone, estradiol)XXX
Metabolism (e.g. cholesterol, LDL, HDL, insulin, triglycerides)XXX
MetabolomicsXXX
DNA methylationXXX
Transcriptomics (mRNA, miRNA)XXX
Genome-wide association study (GWAS)XXX
Paternal biological samples ---------- Timing of sampling ----------
Pre-pregnancy During pregnancy Post pregnancy
SemenXXX
Whole bloodXXX
SerumXXX
PlasmaXXX
Buffy coatXXX
UrineXXX
HairXXX
NailsXXX
SalivaXXX
Purified DNAX
Purified RNAX
Red blood cellsXXX
FaecesXXX
Comments and ideas