• Cohort, name
    Odense Child Cohort

    Cohort, abbreviation


    Cohort, country
    Denmark (Danmark)

    Cohort, website
    http://www.odense.dk/odensekohorten

    Cohort, facebook-site
    OUH - Odense Børnekohorte

    Date of filling in this questionnaire:
    2017-06-21

  • Principal investigator(s), name
    Henriette Boye Kyhl

    Principal investigator(s), e-mail address
    henriette.kyhl@rsyd.dk

    Principal investigator(s), institution
    Odense University Hospital, Hans Christian Andersen Children's Hospital, Paediatric Research Unit

    Contact person(s), name
    Henriette Boye Kyhl

    Contact person(s), e-mail address
    Henriette.kyhl@rsyd.dk

    Contact person(s), institution address
    Odense University Hospital, Hans Christian Andersen Children's Hospital, Paediatric Research Unit

  • Main aim of cohort
    The overall aim of the project is to obtain information on the interaction between the fetus/infant/child during pregnancy, birth and childhood and the social and environmental determinants for health and disease.

    Recruited number of:
    2553 children / 2874 mothers / 2693 fathers / 0 grand parents / 0 other family members

    Approximate proportion of source population included
    43

    Source population
    Other, please describeCity

  • Period of enrollment
    Start: 2010-01-01, End: 2012-12-31

    Enrollment period
    Pregnancy, week 10 to 42

    Enrollment criteria, please specify
    Living in the municipality of Odense

    Exclusion criteria, please specify
    Moving from the municipality of Odense before birth

    Planned age of children at end of follow-up
    18 years
General information ---------- Child age (years) at assessment ----------
<1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Home addressX
School addressX
Birth outcomes
Birth weightX
Birth lengthX
Gestational age at birthX
Apgar scoreX
Congenital malformations
Stillbirth (>= 22 weeks)X
Child’s sexX
Head circumference
Biparietal diameter
Child exposures ---------- Child age (years) at assessment ----------
<1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Breast feedingXX
DietXXXXX
Dietary supplementsXX
Childcare attendanceX
Active smoking
Passive smokingXXXX
Alcohol consumption
Physical activityXXXXX
Substance use
Medicine intakeXXXXX
VaccinationsXXXX
Psychological distress (e.g. bullying)X
Air pollution
Access to green spaces
Built environmentXX
Noise
Radiation, electromagnetic fields
Water contamination
PetsXXX
Farm animal exposure
Biomarkers of exposure
Mercury
Lead
Cadmium
Arsenic
Other metals
Polychlorinated biphenyl esters
Dicloro difenil tricloroetano
Hexachlorobenzene
Brominated flame retardants
Perflouralkyl compounds
Bisphenol A
Other bisphenols
Parabens
Benzophenones
Triclosan
Phthalates
CotinineX
Child development and health ---------- Child age (years) at assessment ----------
<1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Anthropometry
WeightXXXXX
HeightXXXXX
Head circumferenceXXXX
Abdominal circumferenceXXXX
Arm circumference
Wrist circumferenceX
Waist circumference
Clinical examinations
Blood pressureXXXXX
Carotida intima media thickness
Pulse wave velocity
Cardiac ultrasound
Renal ultrasound
Brain MRI
Other MRI
DEXA‐scan resultsX
Skin foldsXXXXX
Bio impedence
Oscilometry
Spirometry
Skin prick test
Bronchial challenge test
Reversibility test
Dental observationsXX
Mental and neurological development
Cognitive functionX
School performanceX
LanguageXX
ADHDX
AutismX
Sleep disturbancesXX
Mental healthXXX
Respiratory health
AsthmaXXX
AllergyXX
Allergic rhinitis
EczemaXX
Respiratory tract infectionsXX
Senses
Vision
Hearing
Musculo-skeletal health
Back pain
Neck pain
Growing painsXX
Sexual maturation
Tanner stage
Pubertal development stage
Age at menarche
Age at voice change
2D/4D digit ratio
Nocturnal ejaculation
Acne
Other health outcomes
Cancer
Diabetes
Congenital anomalies
Biomarkers of health
Nephrology (e.g. creatinine, albumin)
Thyroid hormones
Inflammatory markers (e.g. C-reactive protein cytokines)
Immunologic markers (e.g. immunoglobulines)
CortisolX
Vitamines and micronutrients
Gonadal axis hormones (e.g. testosterone, estradiol)
Metabolism (e.g. cholesterol, LDL, HDL, insulin, triglycerides)XXX
Metabolomics
DNA methylation
Transcriptomics (mRNA, miRNA)
Genome-wide association study (GWAS)
Child biological samples ---------- Child age (years) at sampling ----------
At birth 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Whole bloodX
SerumXXXXXX
PlasmaXXXXXX
Buffy coatX
UrineXX
HairXX
TeethXX
Nails
SalivaX
Purified DNAXX
Purified RNA
Red blood cells
Umbilical cord blood/tissueX
Blood smear
Faeces/meconiumXX
Exhaled breathe condensate
Sputum induction
Placenta
General information
Pre-pregnancy During pregnancy <1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
EducationX
Income
Employment status
Job title
Single parenthoodX
Home address
Work address
Maternal characteristics related to the index pregnancy/child
Age at birthX
EthnicityX
Country of birth
Planned pregnancyX
Time to pregnancyX
Fertility treatmentX
Prior spontaneous abortion (<22w)X
Prior birthsX
Ultrasound measurements
Doppler measurements
Preeclampsia
Gestational diabetes
Gestational hypertension
Gestational durationX
Mode of deliveryX
Prenatal diagnosticsX
Medical termination of pregnancyX
Maternal Exposures ---------- Timing of assessment ----------
Pre-pregnancy First trimester Second trimester Third trimester Post pregnancy
DietXXX
Dietary supplementsXXX
Active smokingXXX
Passive smokingX
Alcohol consumptionXXX
Physical activityXXX
Substance useXX
Medicine intakeXXX
Coffee drinkingXXX
Psychological distress (e.g. life-events, health behaviors, perceived stress)XXX
Occupational exposuresX
Heavy lifts
Work hours
Air pollution
Access to green spaces
Built environment
Noise
Radiation, electromagnetic fields
Water contaminationXX
Binge drinkingXX
PetsX
Farm animal exposure
Biomarkers of exposure
Mercury
Lead
Cadmium
Arsenic
Other metals
Polychlorinated biphenyl esters
Dicloro difenil tricloroetano
Hexachlorobenzene
Brominated flame retardants
Perflouralkyl compounds
Bisphenol A
Other bisphenols
Parabens
Benzophenones
Triclosan
Phthalates
Cotinine
Maternal health ---------- Timing of assessment ----------
Pre-pregnancy First trimester Second trimester Third trimester Post pregnancy
Anthropometry
WeightXXX
HeightXX
Waist circumference
Clinical examinations
Blood pressureXXX
Carotida intima media thickness
Pulse wave velocity
DEXA scans
Bioimpedence
Mental and neurological development
Mental healthXX
Cognitive function (e.g. intelligence quotient)
Respiratory health
Asthma
Allergy
Musculo‐skeletal disease
Back pain
Neck pain
Arthritis
Other health outcomes
CancerX
DiabetesX
Cardio‐vascular disease
Family history of chronic disease
Infectious disease
Fever
Autoimmune disease
Urinary symptoms
Sexual problems
Sleep disturbance
Biomarkers of health
Nephrology (e.g. creatinine, albumin)
Thyroid hormonesX
Inflammatory markers (e.g. C-reactive protein cytokines)
Immunologic markers (e.g. immunoglobulines)
CortisolX
Vitamines and micronutrients
Gonadal axis hormones (e.g. testosterone, estradiol)
Metabolism (e.g. cholesterol, LDL, HDL, insulin, triglycerides)X
Metabolomics
DNA methylation
Transcriptomics (mRNA, miRNA)
Genome-wide association study (GWAS)
Maternal biological samples ---------- Timing of sampling ----------
Pre-pregnancy First trimester Second trimester Third trimester Post pregnancy
Breast milkX
Whole blood
SerumXX
Plasma
Buffy coat
UrineX
Hair
Nails
Saliva
Purified DNA
Purified RNA
Red blood cells
Faeces
General information
Pre-pregnancy During pregnancy <1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Education
Income
Employment status
Job title
Single parenthood
Home address
Work address
Paternal characteristics related to the index pregnancy/child
Fertility treatment
Age at child's birth
EthnicityX
Country of birth
Paternal exposures ---------- Timing of assessment ----------
Pre-pregnancy During pregnancy Post pregnancy
Diet
Dietary supplements
Active smokingX
Passive smoking
Alcohol consumption
Physical activity
Substance use
Medicine intake
Coffee drinking
Psychological distress (e.g. life-events, health behaviors, perceived stress)
Occupational exposures
Heavy lifts
Work hours
Air pollution
Access to green spaces
Built environment
Noise
Radiation, electromagnetic fields
Water contamination
Binge drinking
Pets
Farm animal exposure
Biomarkers of exposure
Mercury
Lead
Cadmium
Arsenic
Other metals
Polychlorinated biphenyl esters
Dicloro difenil tricloroetano
Hexachlorobenzene
Brominated flame retardants
Perflouralkyl compounds
Bisphenol A
Other bisphenols
Parabens
Benzophenones
Triclosan
Phthalates
Cotinine
Paternal health ---------- Timing of assessment ----------
Pre-pregnancy During pregnancy Post pregnancy
Anthropometry
WeightX
HeightX
Waist circumference
Clinical examinations
Blood pressure
Carotida intima media thickness
Pulse wave velocity
DEXA scans
Bio impedence
Mental and neurological development
Mental health
Cognitive function (e.g. intelligence quotient)
Respiratory health
Asthma
Allergy
Musculo‐skeletal disease
Back pain
Neck pain
Arthritis
Other health outcomes
Cancer
Diabetes
Cardio‐vascular disease
Family history of chronic disease
Infectious disease
Fever
Autoimmune disease
Urinary symptoms
Sexual problems
Sleep disturbance
Biomarkers of health
Nephrology (e.g. creatinine, albumin)
Thyroid hormones
Inflammatory markers (e.g. C-reactive protein cytokines)
Immunologic markers (e.g. immunoglobulines)
Cortisol
Vitamines and micronutrients
Gonadal axis hormones (e.g. testosterone, estradiol)
Metabolism (e.g. cholesterol, LDL, HDL, insulin, triglycerides)
Metabolomics
DNA methylation
Transcriptomics (mRNA, miRNA)
Genome-wide association study (GWAS)
Paternal biological samples ---------- Timing of sampling ----------
Pre-pregnancy During pregnancy Post pregnancy
Semen
Whole blood
SerumX
Plasma
Buffy coat
Urine
HairX
Nails
Saliva
Purified DNA
Purified RNA
Red blood cells
Faeces
Comments and ideas
We have 17 subprojects: Exposure to endocrine disrupting chemicals Impact of hormonal and metabolic factors in pregnacy and neonatal health Prenatal exposure to ethanol and long-term effects Study on breastfeeding The role of vitamin D in pregnant and offspring Infections in early childhood Language development in Danish children Oral health in children Establishment of pediatric reference intervals Study of Preschool ADHD Risk Indicators Mothers health and child obesity Religion and health Exposure to pesticids. Effects on children Incidense of intestinal parasites in faeces Risk factors for Filaggrin Expression and Atopic Dermatitis Long-term health risk of excessive screen media use in children Neuropsychological development in schoolchildren